Preparation, characterization and optimization of carbamazepine based pellets prepared by extrusion-spheronization technique

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dc.contributor.advisorKhamanga, S M M
dc.contributor.advisorWalker, Roderick
dc.contributor.authorMakoni, Kudzai Gabriella
dc.date.accessioned2026-03-04T14:38:14Z
dc.date.issued20-Apr
dc.description.abstractCarbamazepine (CBZ) is an oral antiepileptic drug (AED) that is prescribed as a first-line treatment for partial seizures. CBZ is a class II compound according to the Biopharmaceutical Classification System (BCS), hence it exhibits low aqueous solubility and high gastrointestinal tract (GIT) permeability...
dc.description.degreeMaster's thesis
dc.description.degreeMSc (Pharmacy)
dc.format.extent216 pages
dc.format.mimetypeapplication/pdf
dc.identifier.otherhttp://hdl.handle.net/10962/140478
dc.identifier.urihttps://researchrepository.ru.ac.za/handle/123456789/7436
dc.languageEnglish
dc.publisherRhodes University, Faculty of Pharmacy, Pharmacy
dc.rightsMakoni, Kudzai Gabriella
dc.subjectCarbamazepine
dc.subjectPharmacokinetics
dc.subjectAnticonvulsants
dc.subjectDrugs -- Controlled release
dc.subjectDrugs -- Dosage forms
dc.subjectTablets (Medicine)
dc.subjectDrugs -- Administration
dc.subjectHigh performance liquid chromatography
dc.subjectInternational Conference on Harmonisation
dc.subjectExperimental design
dc.titlePreparation, characterization and optimization of carbamazepine based pellets prepared by extrusion-spheronization technique
dc.typeAcademic thesis

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