In vitro investigation of the potential of Bidens pilosa extracts for anti-Alzheimer activity

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dc.contributor.advisorMothibe, Mmamosheledi Elsie
dc.contributor.advisorSibiya, Ntethelelo
dc.contributor.authorChipomho, Leseli
dc.copyrightDate2025
dc.date.accessioned2026-03-18T13:30:28Z
dc.dateIssued2025-10-10
dc.description.abstractAlzheimer’s disease (AD) is a neurocognitive decline disease with no cure and has multiple aetiologies. Currently, available treatment is single-targeted, and disease management is through polypharmacy, which is costly and burdensome to both the patient and caregiver. Bidens pilosa (B. pilosa) is a widely distributed plant reported to have pharmacological effects on over 40 diseases, chiefly attributed to its flavonoid and polyacetylene phytochemicals.
dc.description.degreeMaster of Science
dc.description.degreeMaster's theses
dc.description.degreelevelMaster's
dc.digitalOriginborn digital
dc.disciplinePharmacology
dc.extent1 online resource (118 pages)
dc.formpdf
dc.form.carrieronline resource
dc.form.mediacomputer
dc.identifier.otherChipomho, Leseli (https://orcid.org/0000-0001-7400-1100) [Rhodes University]
dc.identifier.otherMothibe, Mmamosheledi Elsie (https://orcid.org/0000-0002-8613-2543) [Rhodes University]
dc.identifier.otherSibiya, Ntethelelo (https://orcid.org/0000-0001-5894-8935) [Rhodes University]
dc.identifier.urihttps://researchrepository.ru.ac.za/handle/123456789/9959
dc.internetMediaTypeapplication/pdf
dc.language.isoeng
dc.language.isoEnglish
dc.note.thesisThesis (MSc) -- Faculty of Pharmacy, Pharmacy, 2025
dc.placeTerm.codesa
dc.placeTerm.textSouth Africa
dc.publisherRhodes University
dc.publisherFaculty of Pharmacy, Pharmacy
dc.rightsChipomho, Leseli
dc.rightsUse of this resource is governed by the terms and conditions of the Creative Commons "Attribution-NonCommercial-ShareAlike" License (http://creativecommons.org/licenses/by-nc-sa/2.0/)
dc.subject.ddcBidens pilosa (http://id.loc.gov/authorities/subjects/sh85013920)
dc.subject.ddcAlzheimer's disease (http://id.loc.gov/authorities/subjects/sh85004080)
dc.subject.ddcAcetylcholinesterase (http://id.loc.gov/authorities/subjects/sh92004641)
dc.subject.ddcAmyloid beta-protein precursor (http://id.loc.gov/authorities/subjects/sh92004713)
dc.titleIn vitro investigation of the potential of Bidens pilosa extracts for anti-Alzheimer activity
dc.typeAcademic theses
dc.typeOfResourcetext

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